While many clinicians currently recognize that bisphosphonate usage is associated with osteonecrosis of the jaws, this book establishes the causal relationship between the two, explaining the biologic modes of action that enable bisphosphonates taken both orally and intravenously to induce osteonecrosis of the jaws.

Like the first edition, it presents definitive treatment protocols for patients who present at each stage in the progression of osteonecrosis, but this new edition also includes a simplified staging system and information about the serum CTX test for oral bisphosphonate cases.